MDS

MDS

 Canhelp® MDS is a benchtop, automated micro-dissection system that enriches tumor cells from pathology slides for downstream molecular testing. By combining digital pathology (ROI mapping) with a precision robotic scraper, it selectively collects tissue from tumor-rich areas while minimizing contamination from adjacent normal tissue. The result is high-purity input for assays such as TMB, MSI, LOH, and gene-expression profiling—often boosting tumor content from <10% on the original slide to >60% in the collected sample and improving diagnostic accuracy and consistency.

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Key features

  • Automated tumor enrichment: Robotic micro-dissection of pathologist-defined regions of interest.

  • Digital workflow: Software-assisted ROI annotation and precise cutting-path planning.

  • Higher tumor fraction: Output tissue commonly exceeds 60% tumor cells, even from low-tumor slides.

  • Clean sampling: Minimizes carryover/contamination from adjacent non-tumor tissue.

  • Streamlined process (1–4 slides/run):

    1. Load slides → 2) ROI mapping → 3) Automated dissection → 4) Collect/wash into tubes.

  • Use cases: Optimizes input for TMB, MSI, LOH, gene expression and other NGS/PCR-based assays.

Operational benefits: Standardized, reproducible prep; reduced manual labor and subjectivity; faster path-to-result for molecular diagnostics.